METAL IONS/NUCLEOTIDE COORDINATED NANOPARTICLES COMPREHENSIVELY SUPPRESS TUMOR BY SYNERGIZING FERROPTOSIS WITH ENERGY METABOLISM INTERFERENCE

Metal ions/nucleotide coordinated nanoparticles comprehensively suppress tumor by synergizing ferroptosis with energy metabolism interference

Abstract Background Ferroptosis holds promise as a potential tumor therapy by programming cell death with a hallmark of reactive oxygen species (ROS)-induced lipid peroxidation.However, vigorous energy metabolism may assist tumors to resist oxidative damage and thus weaken the effects of ferroptosis in tumor treatment.Results Herein, a bifunctional

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nPPoS: Non-interactive practical proof-of-storage for blockchain

Blockchain full nodes Tweed Waistcoats are pivotal for transaction availability, as they store the entire ledger, but verifying their storage integrity faces challenges from malicious remote storage attacks such as Sybil, outsourcing, and generation attacks.However, there is no suitable proof-of-storage solution for blockchain full nodes to ensure

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Efficient Characterization of Tetraploid Watermelon

Watermelon (Citrullus lanatus (Thunb.) Matsum.&Nakai) is an economic crop, which is widely cultivated around the world.The ploidy study of watermelon has an important role in field breeding and production, therefore, timely and convenient ploidy detection is necessary to accelerate its application.Traditionally, the ploidy of watermelon was det

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